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Src-like Adaptor Protein Regulates Osteoclast Generation and Survival
Src-like adaptor protein (SLAP) is a hematopoietic adaptor containing Src homology (SH)3 and SH2 motifs and a unique carboxy terminus. Unlike c-Src, SLAP lacks a tyrosine kinase domain. We investigated the role of SLAP in osteoclast development and resorptive function. Employing SLAP-deficient mice,...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3680130/ https://ncbi.nlm.nih.gov/pubmed/20225239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22527 |
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