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Synaptotagmin VII Regulates Bone Remodeling by Modulating Osteoclast and Osteoblast Secretion

Maintenance of bone mass and integrity requires a tight balance between resorption by osteoclasts and formation by osteoblasts. Exocytosis of functional proteins is a prerequisite for the activity of both cells. In the present study, we show that synaptotagmin VII, a calcium sensor protein that regu...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zhao, Haibo, Ito, Yuji, Chappel, Jean, Andrews, Norma W., Teitelbaum, Steven L., Ross, F. Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480494/
https://ncbi.nlm.nih.gov/pubmed/18539119
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2008.03.022
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