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Fyn Promotes Proliferation, Differentiation, Survival and Function of Osteoclast Lineage Cells

c-Src and Lyn are the only Src family kinases (SFKs) with established activity in osteoclasts (OCs). c-Src promotes function via cytoskeletal organization of the mature resorptive cell while Lyn is a negative regulator of osteoclastogenesis. We establish that Fyn, another SFK, also impacts the OC, b...

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Autori principali: Kim, Hyun-Ju, Warren, Julia, Kim, Shin-Yoon, Chappel, Jean C., DeSelm, Carl, Ross, F. Patrick, Zou, Wei, Teitelbaum, Steven L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3719388/
https://ncbi.nlm.nih.gov/pubmed/20717919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22841
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