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Peroxisome Proliferator-activated Receptor-α-mediated Transcription of miR-199a2 Attenuates Endothelin-1 Expression via Hypoxia-inducible Factor-1α

Endothelin-1, a potent vasoconstrictor, plays an important role in pulmonary hypertension (PH) in sickle cell disease (SCD). Our previous studies show that higher levels of placenta growth factor (PlGF), secreted by erythroid precursor cells, correlate with increased plasma levels of endothelin-1 (E...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Biol Chem
मुख्य लेखकों: Li, Chen, Mpollo, Marthe-Sandrine Eiymo Mwa, Gonsalves, Caryn S., Tahara, Stanley M., Malik, Punam, Kalra, Vijay K.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2014
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276869/
https://ncbi.nlm.nih.gov/pubmed/25389292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.600775
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