MicroRNA 648 Targets ET-1 mRNA and Is Cotranscriptionally Regulated with MICAL3 by PAX5

Pulmonary hypertension (PHT) is associated with high mortality in sickle cell anemia (SCA). Previously, we showed that elevated levels of placenta growth factor (PlGF) in SCA patients correlate with increased levels of the potent vasoconstrictor endothelin-1 (ET-1) and PHT. Moreover, PlGF induced th...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Li, Chen, Gonsalves, Caryn S., Eiymo Mwa Mpollo, Marthe-Sandrine, Malik, Punam, Tahara, Stanley M., Kalra, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4285416/
https://ncbi.nlm.nih.gov/pubmed/25403488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01199-14
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