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Placenta growth factor augments endothelin-1 and endothelin-B receptor expression via hypoxia-inducible factor-1α
Pulmonary hypertension (PHT) develops in sickle cell disease (SCD) and is associated with high mortality. We previously showed that erythroid cells produce placenta growth factor (PlGF), which activates monocytes to induce proinflammatory cytochemokines, contributing to the baseline inflammation and...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2481529/ https://ncbi.nlm.nih.gov/pubmed/18411415 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-12-130567 |
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