Real-time Detection of Hepatic Gluconeogenic and Glycogenolytic States Using Hyperpolarized [2-(13)C]Dihydroxyacetone

Glycogenolysis and gluconeogenesis are sensitive to nutritional state, and the net direction of flux is controlled by multiple enzymatic steps. This delicate balance in the liver is disrupted by a variety of pathological states including cancer and diabetes mellitus. Hyperpolarized carbon-13 magneti...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Moreno, Karlos X., Satapati, Santhosh, DeBerardinis, Ralph J., Burgess, Shawn C., Malloy, Craig R., Merritt, Matthew E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276855/
https://ncbi.nlm.nih.gov/pubmed/25352600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.613265
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