1,25(OH)(2)D(3) Induces a Mineralization Defect and Loss of Bone Mineral Density in Genetic Hypercalciuric Stone-Forming Rats

Genetic hypercalciuric stone-forming (GHS) rats, bred to maximize urine (u) calcium (Ca) excretion, demonstrate increased intestinal Ca absorption, increased bone Ca resorption and reduced renal Ca reabsorption, all leading to elevated uCa compared to the parental Sprague-Dawley (SD) rats. GHS rats...

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Publicado en:Calcif Tissue Int
Main Authors: Ng, Adeline H., Frick, Kevin K., Krieger, Nancy S., Asplin, John R., Cohen-McFarlane, Madison, Culbertson, Christopher D., Kyker-Snowman, Kelly, Grynpas, Marc D., Bushinsky, David A.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276134/
https://ncbi.nlm.nih.gov/pubmed/24481706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-014-9838-7
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