Chlorthalidone Improves Vertebral Bone Quality in Genetic Hypercalciuric Stone-Forming Rats

We have bred a strain of rats to maximize urine (U) calcium (Ca) excretion and model hypercalciuric nephrolithiasis. These genetic hypercalciuric stone-forming (GHS) rats excrete more UCa than control Sprague-Dawley rats, uniformly form kidney stones and, similar to patients, demonstrate lower bone...

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Udgivet i:J Bone Miner Res
Main Authors: Bushinsky, David A., Willett, Thomas, Asplin, John R., Culbertson, Christopher, Che, Sara P.Y., Grynpas, Marc
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4493760/
https://ncbi.nlm.nih.gov/pubmed/21351146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.374
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