1,25(OH)(2)D(3) Induces a Mineralization Defect and Loss of Bone Mineral Density in Genetic Hypercalciuric Stone-Forming Rats

Genetic hypercalciuric stone-forming (GHS) rats, bred to maximize urine (u) calcium (Ca) excretion, demonstrate increased intestinal Ca absorption, increased bone Ca resorption and reduced renal Ca reabsorption, all leading to elevated uCa compared to the parental Sprague-Dawley (SD) rats. GHS rats...

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Bibliografske podrobnosti
izdano v:Calcif Tissue Int
Main Authors: Ng, Adeline H., Frick, Kevin K., Krieger, Nancy S., Asplin, John R., Cohen-McFarlane, Madison, Culbertson, Christopher D., Kyker-Snowman, Kelly, Grynpas, Marc D., Bushinsky, David A.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4276134/
https://ncbi.nlm.nih.gov/pubmed/24481706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00223-014-9838-7
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