Persistence of 1,25D-induced hypercalciuria in alendronate-treated genetic hypercalciuric stone-forming rats fed a low-calcium diet

Genetic hypercalciuric stone-forming (GHS) rats demonstrate increased intestinal Ca absorption, increased bone resorption, and reduced renal tubular Ca reabsorption leading to hypercalciuria and all form kidney stones. GHS have increased vitamin D receptors (VDR) at these sites of Ca transport. Inje...

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Bibliographic Details
Main Authors: Frick, Kevin K., Asplin, John R., Culbertson, Christopher D., Granja, Ignacio, Krieger, Nancy S., Bushinsky, David A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4010677/
https://ncbi.nlm.nih.gov/pubmed/24573387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00680.2013
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