Chlorthalidone Is Superior to Potassium Citrate in Reducing Calcium Phosphate Stones and Increasing Bone Quality in Hypercalciuric Stone-Forming Rats

BACKGROUND: The pathophysiology of genetic hypercalciuric stone-forming rats parallels that of human idiopathic hypercalciuria. In this model, all animals form calcium phosphate stones. We previously found that chlorthalidone, but not potassium citrate, decreased stone formation in these rats. METHO...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Krieger, Nancy S., Asplin, John R., Granja, Ignacio, Ramos, Felix M., Flotteron, Courtney, Chen, Luojing, Wu, Tong Tong, Grynpas, Marc D., Bushinsky, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2019
Assuntos:
Basic Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6622425/
https://ncbi.nlm.nih.gov/pubmed/31101664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2018101066
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