Bioactive conformation of stromelysin inhibitors determined by transferred nuclear Overhauser effects.

The transferred nuclear Overhauser effect has been used to determine the biologically active conformations of two stromelysin inhibitors. Both inhibitors used in this study were hydroxamic acids generated via chemical synthesis. These structures, representing the conformation of each inhibitor bound...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Gonnella, N C, Bohacek, R, Zhang, X, Kolossváry, I, Paris, C G, Melton, R, Winter, C, Hu, S I, Ganu, V
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1995
主題:	Research Article
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7831311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.2.462
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