Bioactive conformation of stromelysin inhibitors determined by transferred nuclear Overhauser effects.

The transferred nuclear Overhauser effect has been used to determine the biologically active conformations of two stromelysin inhibitors. Both inhibitors used in this study were hydroxamic acids generated via chemical synthesis. These structures, representing the conformation of each inhibitor bound...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Gonnella, N C, Bohacek, R, Zhang, X, Kolossváry, I, Paris, C G, Melton, R, Winter, C, Hu, S I, Ganu, V
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7831311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.2.462
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