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Bioactive conformation of stromelysin inhibitors determined by transferred nuclear Overhauser effects.

The transferred nuclear Overhauser effect has been used to determine the biologically active conformations of two stromelysin inhibitors. Both inhibitors used in this study were hydroxamic acids generated via chemical synthesis. These structures, representing the conformation of each inhibitor bound...

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Dettagli Bibliografici
Autori principali: Gonnella, N C, Bohacek, R, Zhang, X, Kolossváry, I, Paris, C G, Melton, R, Winter, C, Hu, S I, Ganu, V
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1995
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC42760/
https://ncbi.nlm.nih.gov/pubmed/7831311
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