Bioactive conformation of stromelysin inhibitors determined by transferred nuclear Overhauser effects.

The transferred nuclear Overhauser effect has been used to determine the biologically active conformations of two stromelysin inhibitors. Both inhibitors used in this study were hydroxamic acids generated via chemical synthesis. These structures, representing the conformation of each inhibitor bound...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Gonnella, N C, Bohacek, R, Zhang, X, Kolossváry, I, Paris, C G, Melton, R, Winter, C, Hu, S I, Ganu, V
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1995
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42760/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7831311/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.2.462
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