Bioactive conformation of stromelysin inhibitors determined by transferred nuclear Overhauser effects.

The transferred nuclear Overhauser effect has been used to determine the biologically active conformations of two stromelysin inhibitors. Both inhibitors used in this study were hydroxamic acids generated via chemical synthesis. These structures, representing the conformation of each inhibitor bound...

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Detalhes bibliográficos
Main Authors: Gonnella, N C, Bohacek, R, Zhang, X, Kolossváry, I, Paris, C G, Melton, R, Winter, C, Hu, S I, Ganu, V
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42760/
https://ncbi.nlm.nih.gov/pubmed/7831311
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