Gene Expression of Mesothelioma in Vinylidene Chloride-Exposed F344/N Rats Reveals Immune Dysfunction, Tissue Damage, and Inflammation Pathways

A majority (~80%) of human malignant mesotheliomas are asbestos-related. However, non-asbestos risk factors (radiation, chemicals, genetic factors) account for up to 30% of cases. A recent two-year National Toxicology Program carcinogenicity bioassay showed that male F344/N rats exposed to the indus...

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Gepubliceerd in:Toxicol Pathol
Hoofdauteurs: Blackshear, Pamela E., Pandiri, Arun R., Nagai, Hiroaki, Bhusari, Sachin, Hong, Lily, Ton, Thai-Vu T., Clayton, Natasha P., Wyde, Michael, Shockley, Keith R., Peddada, Shyamal D., Gerrish, Kevin E., Sills, Robert C., Hoenerhoff, Mark J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275413/
https://ncbi.nlm.nih.gov/pubmed/24958746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0192623314537885
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