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Cyclic Nucleotide Phosphodiesterases: important signaling modulators and therapeutic targets

By catalyzing hydrolysis of cAMP and cGMP, cyclic nucleotide phosphodiesterases are critical regulators of their intracellular concentrations and their biological effects. Since these intracellular second messengers control many cellular homeostatic processes, dysregulation of their signals and sign...

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Detalhes bibliográficos
Publicado no:Oral Dis
Main Authors: Ahmad, Faiyaz, Murata, Taku, Simizu, Kasumi, Degerman, Eva, Maurice, Donald, Manganiello, Vincent
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4275405/
https://ncbi.nlm.nih.gov/pubmed/25056711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/odi.12275
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