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Mitochondrial proteostasis in the control of aging and longevity

Mitochondria play a central role in the aging process. Studies in model organisms have started to integrate mitochondrial effects on aging with the maintenance of protein homeostasis. These findings center on the mitochondrial unfolded protein response (UPR(mt)), which has been implicated in lifespa...

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Bibliografiske detaljer
Udgivet i:Cell Metab
Main Authors: Jensen, Martin Borch, Jasper, Heinrich
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274350/
https://ncbi.nlm.nih.gov/pubmed/24930971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.05.006
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