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Mitochondrial proteostasis in the control of aging and longevity

Mitochondria play a central role in the aging process. Studies in model organisms have started to integrate mitochondrial effects on aging with the maintenance of protein homeostasis. These findings center on the mitochondrial unfolded protein response (UPR(mt)), which has been implicated in lifespa...

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Detalles Bibliográficos
Publicado en:Cell Metab
Main Authors: Jensen, Martin Borch, Jasper, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado: 2014
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274350/
https://ncbi.nlm.nih.gov/pubmed/24930971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.05.006
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