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Mitochondrial proteostasis in the control of aging and longevity

Mitochondria play a central role in the aging process. Studies in model organisms have started to integrate mitochondrial effects on aging with the maintenance of protein homeostasis. These findings center on the mitochondrial unfolded protein response (UPR(mt)), which has been implicated in lifespa...

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Publicat a:Cell Metab
Autors principals: Jensen, Martin Borch, Jasper, Heinrich
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274350/
https://ncbi.nlm.nih.gov/pubmed/24930971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2014.05.006
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