JNK modifies neuronal metabolism to promote proteostasis and longevity

Aging is associated with a progressive loss of tissue and metabolic homeostasis. This loss can be delayed by single‐gene perturbations, increasing lifespan. How such perturbations affect metabolic and proteostatic networks to extend lifespan remains unclear. Here, we address this question by compreh...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Wang, Lifen, Davis, Sonnet S., Borch Jensen, Martin, Rodriguez‐Fernandez, Imilce A., Apaydin, Cagsar, Juhasz, Gabor, Gibson, Bradford W., Schilling, Birgit, Ramanathan, Arvind, Ghaemmaghami, Sina, Jasper, Heinrich
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Original Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6516429/
https://ncbi.nlm.nih.gov/pubmed/30810280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12849
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