Molecular Markers Identify Subtypes of Stage III Colon Cancer Associated with Patient Outcomes

BACKGROUND & AIMS: Categorization of colon cancers into distinct subtypes using a combination of pathway-based biomarkers could provide insight into stage-independent variability in outcomes. METHODS: We used a PCR-based assay to detect mutations in BRAF (V600E) and in KRAS in 2720 stage III can...

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Publicado en:Gastroenterology
Autores principales: Sinicrope, Frank A., Shi, Qian, Smyrk, Thomas C., Thibodeau, Stephen N., Dienstmann, Rodrigo, Guinney, Justin, Bot, Brian M., Tejpar, Sabine, Delorenzi, Mauro, Goldberg, Richard M., Mahoney, Michelle, Sargent, Daniel J., Alberts, Steven R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274188/
https://ncbi.nlm.nih.gov/pubmed/25305506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.09.041
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