Molecular Markers Identify Subtypes of Stage III Colon Cancer Associated with Patient Outcomes

BACKGROUND & AIMS: Categorization of colon cancers into distinct subtypes using a combination of pathway-based biomarkers could provide insight into stage-independent variability in outcomes. METHODS: We used a PCR-based assay to detect mutations in BRAF (V600E) and in KRAS in 2720 stage III can...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Gastroenterology
Main Authors: Sinicrope, Frank A., Shi, Qian, Smyrk, Thomas C., Thibodeau, Stephen N., Dienstmann, Rodrigo, Guinney, Justin, Bot, Brian M., Tejpar, Sabine, Delorenzi, Mauro, Goldberg, Richard M., Mahoney, Michelle, Sargent, Daniel J., Alberts, Steven R.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274188/
https://ncbi.nlm.nih.gov/pubmed/25305506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2014.09.041
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki