Trpm4 Gene Invalidation Leads to Cardiac Hypertrophy and Electrophysiological Alterations

RATIONALE: TRPM4 is a non-selective Ca(2+)-activated cation channel expressed in the heart, particularly in the atria or conduction tissue. Mutations in the Trpm4 gene were recently associated with several human conduction disorders such as Brugada syndrome. TRPM4 channel has also been implicated at...

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Udgivet i:PLoS One
Main Authors: Demion, Marie, Thireau, Jérôme, Gueffier, Mélanie, Finan, Amanda, Khoueiry, Ziad, Cassan, Cécile, Serafini, Nicolas, Aimond, Franck, Granier, Mathieu, Pasquié, Jean-Luc, Launay, Pierre, Richard, Sylvain
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274076/
https://ncbi.nlm.nih.gov/pubmed/25531103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115256
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