9-Phenanthrol inhibits human TRPM4 but not TRPM5 cationic channels

Background and purpose: TRPM4 and TRPM5 are calcium-activated non-selective cation channels with almost identical characteristics. TRPM4 is detected in several tissues including heart, kidney, brainstem, cerebral artery and immune system whereas TRPM5 expression is more restricted. Determination of...

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Autors principals: Grand, T, Demion, M, Norez, C, Mettey, Y, Launay, P, Becq, F, Bois, P, Guinamard, R
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2008
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2438271/
https://ncbi.nlm.nih.gov/pubmed/18297105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.38
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