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Fluorinated Aromatic Amino Acids Are Sensitive (19)F NMR Probes for Bromodomain-Ligand Interactions
[Image: see text] We describe a (19)F NMR method for detecting bromodomain–ligand interactions using fluorine-labeled aromatic amino acids due to the conservation of aromatic residues in the bromodomain binding site. We test the sensitivity, accuracy, and speed of this method with small molecule lig...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | ACS Chem Biol |
|---|---|
| Prif Awduron: | , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
American Chemical
Society
2014
|
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273984/ https://ncbi.nlm.nih.gov/pubmed/25290579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5007344 |
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