Identification of Small Molecules That Protect Pancreatic β Cells against Endoplasmic Reticulum Stress-Induced Cell Death

[Image: see text] Endoplasmic reticulum (ER) stress plays an important role in the decline in pancreatic β cell function and mass observed in type 2 diabetes. Here, we developed a novel β cell-based high-throughput screening assay to identify small molecules that protect β cells against ER stress-in...

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Vydáno v:ACS Chem Biol
Hlavní autoři: Tran, Kim, Li, Yu, Duan, Hongliang, Arora, Daleep, Lim, Hui-Ying, Wang, Weidong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273981/
https://ncbi.nlm.nih.gov/pubmed/25279668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500740d
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