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Glucotoxic conditions induce endoplasmic reticulum stress to cause caspase 3 mediated lamin B degradation in pancreatic β-cells: Protection by nifedipine

Nuclear lamins form the lamina on the interior of the nuclear envelope, and are involved in the regulation of various cellular processes, including DNA replication and chromatin organization. Despite this evidence, little is known about potential alterations in nuclear metabolism, specifically lamin...

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Detalhes bibliográficos
Main Authors: Syeda, Khadija, Mohammed, Abiy M., Arora, Daleep K., Kowluru, Anjaneyulu
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832847/
https://ncbi.nlm.nih.gov/pubmed/23994168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2013.08.023
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