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iPS Cell-Derived Cardiogenicity is Hindered by Sustained Integration of Reprogramming Transgenes
BACKGROUND: Nuclear reprogramming inculcates pluripotent capacity by which de novo tissue differentiation is enabled. Yet, introduction of ectopic reprogramming factors may desynchronize natural developmental schedules. This study aims to evaluate the impact of imposed transgene load on the cardioge...
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| Pubblicato in: | Circ Cardiovasc Genet |
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| Autori principali: | , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273857/ https://ncbi.nlm.nih.gov/pubmed/25077947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.113.000298 |
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