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iPS Programmed Without c-MYC Yield Proficient Cardiogenesis for Functional Heart Chimerism

RATIONALE: Induced pluripotent stem cells (iPS) allow derivation of pluripotent progenitors from somatic sources. Originally, iPS were induced by a stemness-related gene set that included the c-MYC oncogene. OBJECTIVE: Here, we determined from embryo to adult the cardiogenic proficiency of iPS progr...

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Detalhes bibliográficos
Main Authors: Martinez-Fernandez, Almudena, Nelson, Timothy J., Yamada, Satsuki, Reyes, Santiago, Alekseev, Alexey E., Perez-Terzic, Carmen, Ikeda, Yasuhiro, Terzic, Andre
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785796/
https://ncbi.nlm.nih.gov/pubmed/19696409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.203109
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