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Crucial role of nonspecific interactions in amyloid nucleation
Protein oligomers have been implicated as toxic agents in a wide range of amyloid-related diseases. However, it has remained unsolved whether the oligomers are a necessary step in the formation of amyloid fibrils or just a dangerous byproduct. Analogously, it has not been resolved if the amyloid nuc...
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| 發表在: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4273401/ https://ncbi.nlm.nih.gov/pubmed/25453085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1410159111 |
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