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FcγRIIb inhibits immune complex-induced VEGF-A production and intranodal lymphangiogenesis

IgG immune complexes (ICs) are generated during immune responses to infection and self-antigen and have been implicated in the pathogenesis of autoimmune diseases such as systemic lupus erythematosus (SLE). Their role, and that of the fragment crystallizable (Fc) receptors that bind them, in driving...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Clatworthy, Menna R., Harford, Sarah K., Mathews, Rebeccah J., Smith, Kenneth G. C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273345/
https://ncbi.nlm.nih.gov/pubmed/25475856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413915111
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