FcγRIIb on liver sinusoidal endothelium clears small immune complexes

It has long been known that the ITIM-bearing IgG Fc receptor (FcγRIIb, RIIb) is expressed on liver sinusoidal endothelial cells (LSEC) and that the liver is the major site of small immune complex (SIC) clearance. Thus, we proposed that RIIb of LSEC eliminates blood-borne small immune complexes (SIC)...

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Publicat a:J Immunol
Autors principals: Ganesan, Latha P., Kim, Jonghan, Wu, Yun, Mohanty, Sudhasri, Phillips, Gary S., Birmingham, Daniel J., Robinson, John M., Anderson, Clark L.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4381350/
https://ncbi.nlm.nih.gov/pubmed/23053513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202017
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