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FcRn in the yolk sac endoderm of mouse is required for IgG transport to fetus
In adults the nonclassical MHC-I molecule, FcRn, binds both IgG and albumin and rescues both from a degradative fate, endowing both proteins with high plasma concentrations. FcRn also transports IgG from mother to young during gestation. Anticipating that a detailed understanding of gestational IgG...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2676880/ https://ncbi.nlm.nih.gov/pubmed/19234152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0803247 |
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