Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis

Currently available immunomodulatory therapies do not stop the pathogenesis underlying multiple sclerosis (MS) and are only partially effective in preventing the onset of permanent disability in patients with MS. Identifying a drug that stimulates endogenous remyelination and/or minimizes axonal deg...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Moore, Spencer M., Khalaj, Anna J., Kumar, Shalini, Winchester, Zachary, Yoon, JaeHee, Yoo, Timothy, Martinez-Torres, Leonardo, Yasui, Norio, Katzenellenbogen, John A., Tiwari-Woodruff, Seema Kaushalya
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2014
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273334/
https://ncbi.nlm.nih.gov/pubmed/25453074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411294111
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