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Nudging Oligodendrocyte Intrinsic Signaling to Remyelinate and Repair: Estrogen Receptor Ligand Effects

Demyelination in multiple sclerosis (MS) leads to significant, progressive axonal and neuronal degeneration. Currently existing immunosuppressive and immunomodulatory therapies alleviate MS symptoms and slow, but fail to prevent or reverse, disease progression. Restoration of damaged myelin sheath b...

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Podrobná bibliografie
Vydáno v:J Steroid Biochem Mol Biol
Hlavní autoři: Khalaj, Anna J., Hasselmann, Jonathan, Augello, Catherine, Moore, Spencer, Tiwari-Woodruff, Seema K.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5233753/
https://ncbi.nlm.nih.gov/pubmed/26776441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2016.01.006
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