Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis

BACKGROUND: Therapeutic strategies that induce effective neuroprotection and enhance intrinsic repair mechanisms are central goals for future treatment of multiple sclerosis (MS), as well as other diseases. Laquinimod (LQ) is an orally administered, central nervous system (CNS)-active immunomodulato...

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Detalhes bibliográficos
Main Authors: Moore, Spencer, Khalaj, Anna J, Yoon, JaeHee, Patel, Rhusheet, Hannsun, Gemmy, Yoo, Timothy, Sasidhar, Manda, Martinez-Torres, Leonardo, Hayardeny, Liat, Tiwari-Woodruff, Seema K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2013
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868172/
https://ncbi.nlm.nih.gov/pubmed/24363970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.174
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