Therapeutic laquinimod treatment decreases inflammation, initiates axon remyelination, and improves motor deficit in a mouse model of multiple sclerosis

BACKGROUND: Therapeutic strategies that induce effective neuroprotection and enhance intrinsic repair mechanisms are central goals for future treatment of multiple sclerosis (MS), as well as other diseases. Laquinimod (LQ) is an orally administered, central nervous system (CNS)-active immunomodulato...

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Autors principals: Moore, Spencer, Khalaj, Anna J, Yoon, JaeHee, Patel, Rhusheet, Hannsun, Gemmy, Yoo, Timothy, Sasidhar, Manda, Martinez-Torres, Leonardo, Hayardeny, Liat, Tiwari-Woodruff, Seema K
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2013
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Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3868172/
https://ncbi.nlm.nih.gov/pubmed/24363970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.174
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