Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis

Currently available immunomodulatory therapies do not stop the pathogenesis underlying multiple sclerosis (MS) and are only partially effective in preventing the onset of permanent disability in patients with MS. Identifying a drug that stimulates endogenous remyelination and/or minimizes axonal deg...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Moore, Spencer M., Khalaj, Anna J., Kumar, Shalini, Winchester, Zachary, Yoon, JaeHee, Yoo, Timothy, Martinez-Torres, Leonardo, Yasui, Norio, Katzenellenbogen, John A., Tiwari-Woodruff, Seema Kaushalya
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273334/
https://ncbi.nlm.nih.gov/pubmed/25453074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411294111
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