Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis

Currently available immunomodulatory therapies do not stop the pathogenesis underlying multiple sclerosis (MS) and are only partially effective in preventing the onset of permanent disability in patients with MS. Identifying a drug that stimulates endogenous remyelination and/or minimizes axonal deg...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Moore, Spencer M., Khalaj, Anna J., Kumar, Shalini, Winchester, Zachary, Yoon, JaeHee, Yoo, Timothy, Martinez-Torres, Leonardo, Yasui, Norio, Katzenellenbogen, John A., Tiwari-Woodruff, Seema Kaushalya
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273334/
https://ncbi.nlm.nih.gov/pubmed/25453074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411294111
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