Multiple functional therapeutic effects of the estrogen receptor β agonist indazole-Cl in a mouse model of multiple sclerosis

Currently available immunomodulatory therapies do not stop the pathogenesis underlying multiple sclerosis (MS) and are only partially effective in preventing the onset of permanent disability in patients with MS. Identifying a drug that stimulates endogenous remyelination and/or minimizes axonal deg...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Moore, Spencer M., Khalaj, Anna J., Kumar, Shalini, Winchester, Zachary, Yoon, JaeHee, Yoo, Timothy, Martinez-Torres, Leonardo, Yasui, Norio, Katzenellenbogen, John A., Tiwari-Woodruff, Seema Kaushalya
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4273334/
https://ncbi.nlm.nih.gov/pubmed/25453074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1411294111
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