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Nucleosome positioning is unaltered at MLH1 splice site mutations in cells derived from Lynch syndrome patients
BACKGROUND: Splicing is more efficient when coupled with transcription and it has been proposed that nucleosomes enriched in exons are important for splice site recognition. Lynch syndrome is a familial cancer syndrome that can be caused by the autosomal dominant inheritance of splice site mutations...
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| Publicado no: | Clin Epigenetics |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272815/ https://ncbi.nlm.nih.gov/pubmed/25530820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-014-0032-6 |
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