Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways

Genetic studies show that LRRK2, and not its closest paralogue LRRK1, is linked to Parkinson’s disease. To gain insight into the molecular and cellular basis of this discrepancy, we searched for LRRK1- and LRRK2-specific cellular processes by identifying their distinct interacting proteins. A protei...

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書誌詳細
出版年:J Neurochem
主要な著者: Reyniers, Lauran, Del Giudice, Maria Grazia, Civiero, Laura, Belluzzi, Elisa, Lobbestael, Evy, Beilina, Alexandra, Arrigoni, Giorgio, Derua, Rita, Waelkens, Etienne, Li, Yan, Crosio, Claudia, Iaccarino, Ciro, Cookson, Mark R., Baekelandt, Veerle, Greggio, Elisa, Taymans, Jean-Marc
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272680/
https://ncbi.nlm.nih.gov/pubmed/24947832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12798
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