A computational algorithm to predict shRNA potency

The strength of conclusions drawn from RNAi-based studies is heavily influenced by the quality of tools used to elicit knockdown. Prior studies have developed algorithms to design siRNAs. However, to date, no established method has emerged to identify effective shRNAs, which have lower intracellular...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Mol Cell
Prif Awduron: Knott, Simon R.V., Maceli, Ashley, Erard, Nicolas, Chang, Kenneth, Marran, Krista, Zhou, Xin, Gordon, Assaf, Demerdash, Osama El, Wagenblast, Elvin, Kim, Sun, Fellmann, Christof, Hannon, Gregory J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2014
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272634/
https://ncbi.nlm.nih.gov/pubmed/25435137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2014.10.025
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