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Deregulation of Rb-E2F1 Axis Causes Chromosomal Instability by Engaging the Transactivation Function of Cdc20–Anaphase-Promoting Complex/Cyclosome
The E2F family of transcription factors regulates genes involved in various aspects of the cell cycle. Beyond the well-documented role in G(1)/S transition, mitotic regulation by E2F has also been reported. Proper mitotic progression is monitored by the spindle assembly checkpoint (SAC). The SAC ens...
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| Publicat a: | Mol Cell Biol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272426/ https://ncbi.nlm.nih.gov/pubmed/25368385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00868-14 |
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