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Deregulation of Rb-E2F1 Axis Causes Chromosomal Instability by Engaging the Transactivation Function of Cdc20–Anaphase-Promoting Complex/Cyclosome

The E2F family of transcription factors regulates genes involved in various aspects of the cell cycle. Beyond the well-documented role in G(1)/S transition, mitotic regulation by E2F has also been reported. Proper mitotic progression is monitored by the spindle assembly checkpoint (SAC). The SAC ens...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Nath, Somsubhra, Chowdhury, Abhishek, Dey, Sanjib, Roychoudhury, Anirban, Ganguly, Abira, Bhattacharyya, Dibyendu, Roychoudhury, Susanta
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272426/
https://ncbi.nlm.nih.gov/pubmed/25368385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00868-14
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