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Targeting Hepatitis B Virus With CRISPR/Cas9
Hepatitis B virus persistence in infected hepatocytes is due to the presence of covalently closed circular DNA (cccDNA), the template for the transcription of viral RNAs. Antiviral therapies with nucleoside analogues inhibit replication of HBV DNA in capsids present in the cytoplasm of infected cell...
Kaydedildi:
| Yayımlandı: | Mol Ther Nucleic Acids |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Nature Publishing Group
2014
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4272409/ https://ncbi.nlm.nih.gov/pubmed/25514649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.68 |
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