COSMID: A Web-based Tool for Identifying and Validating CRISPR/Cas Off-target Sites

Precise genome editing using engineered nucleases can significantly facilitate biological studies and disease treatment. In particular, clustered regularly interspaced short palindromic repeats (CRISPR) with CRISPR-associated (Cas) proteins are a potentially powerful tool for modifying a genome by t...

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Bibliografiske detaljer
Udgivet i:Mol Ther Nucleic Acids
Main Authors: Cradick, Thomas J, Qiu, Peng, Lee, Ciaran M, Fine, Eli J, Bao, Gang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2014
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272406/
https://ncbi.nlm.nih.gov/pubmed/25462530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtna.2014.64
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