Detection of Methylated Septin 9 in Tissue and Plasma of Colorectal Patients with Neoplasia and the Relationship to the Amount of Circulating Cell-Free DNA

BACKGROUND: Determination of methylated Septin 9 (mSEPT9) in plasma has been shown to be a sensitive and specific biomarker for colorectal cancer (CRC). However, the relationship between methylated DNA in plasma and colon tissue of the same subjects has not been reported. METHODS: Plasma and matchin...

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Udgivet i:PLoS One
Main Authors: Tóth, Kinga, Wasserkort, Reinhold, Sipos, Ferenc, Kalmár, Alexandra, Wichmann, Barnabás, Leiszter, Katalin, Valcz, Gábor, Juhász, Márk, Miheller, Pál, Patai, Árpád V., Tulassay, Zsolt, Molnár, Béla
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4272286/
https://ncbi.nlm.nih.gov/pubmed/25526039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115415
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