Promoter Hypermethylation-Related Reduced Somatostatin Production Promotes Uncontrolled Cell Proliferation in Colorectal Cancer

BACKGROUND: Somatostatin (SST) has anti-proliferative and pro-apoptotic effects. Our aims were to analyze and compare the SST expression during normal aging and colorectal carcinogenesis at mRNA and protein levels. Furthermore, we tested the methylation status of SST in biopsy samples, and the cell...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Leiszter, Katalin, Sipos, Ferenc, Galamb, Orsolya, Krenács, Tibor, Veres, Gábor, Wichmann, Barna, Fűri, István, Kalmár, Alexandra, Patai, Árpád V., Tóth, Kinga, Valcz, Gábor, Tulassay, Zsolt, Molnár, Béla
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344335/
https://ncbi.nlm.nih.gov/pubmed/25723531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118332
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge