Potential Biomarkers of Colorectal Adenoma–Dysplasia–Carcinoma Progression: mRNA Expression Profiling and In Situ Protein Detection on TMAs Reveal 15 Sequentially Upregulated and 2 Downregulated Genes

Background: As most colorectal cancers (CRC) develop from villous adenomas, studying alterations in gene expression profiles across the colorectal adenoma–dysplasia–carcinoma sequence may yield potential biomarkers of disease progression. Methods: Total RNA was extracted, amplified, and biotinylated...

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Detalhes bibliográficos
Publicado no:Cell Oncol
Main Authors: Galamb, Orsolya, Sipos, Ferenc, Spisák, Sándor, Galamb, Barnabás, Krenács, Tibor, Valcz, Gábor, Tulassay, Zsolt, Molnár, Béla
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618585/
https://ncbi.nlm.nih.gov/pubmed/19096147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2009-0458
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